Uganda has signed a significant Ksh297 billion ($2.3 billion) health cooperation deal with the United States, following closely on the heels of a similar agreement by Kenya. This five-year pact aims to enhance Uganda's health sector with substantial U.S. aid and increased domestic investment.

• The U.S. will provide up to Ksh220 billion ($1.7 billion), with Uganda committing over Ksh64 billion ($500 million) in increased domestic health spending.
• The agreement was signed on Wednesday, December 10, 2025, by Minister of Finance, Planning and Economic Development Matia Kasaija and U.S. Ambassador to Uganda William W. Popp.
• The funds will support critical programs including HIV/AIDS, tuberculosis, malaria, maternal and child health, and disease surveillance.
• Kenya's similar Ksh207 billion ($1.6 billion) deal, signed on December 4, 2025, faced controversy and was suspended by the High Court on Thursday, December 11, 2025, over data sharing concerns.